Plasma Cell Disorders

1.Mott cell

2.A 70-year-old woman admitted with worsening anemia and pathological fracture of the Humerus, had an ESR of 120mm in 1 hour. Her peripheral smear showed increased rouleaux formation. X-ray of skull showed multiple punched out osteolytic lesions.

• a) What is the most probable diagnosis.
• b) Write briefly on the etiopathogenesis of this disease.
• c) Enumerate the common laboratory investigations for this disease

3.Myeloma kidney

4.Russell body

1.Enumerate four common laboratory tests done to confirm Multiple Myeloma

2.Blood and bone marrow picture in multiple myeloma

1.Name the condition associated with Bence-Jones proteinuria

2.Name a diagnostic test in urine in multiple myeloma