Immunodeficiency & AIDS

1.Define AIDS. Describe the etiopathogenesis and lab. diagnosis of the same

1.Opportunistic infections

2.Name two opportunistic infections in AIDS

3.Pathogenesis of HIV infection and AIDS

4.AIDS defining opportunistic infections

5.A 25 years old male drug abuser came to the hospital with generalized lymphadenopathy, chronic diarrhea, loss of weight and mucosal candidiasis. There is a fall in CD4 cell count. Answer the following:

• a) What is your diagnosis
• b) What is the pathogenesis of this condition
• c) Discuss the pathology of the organs involved
• d) List four investigations to be done

6.Opportunistic infections in acquired immunodeficiency syndrome (AIDS)

7.A 30 years old male truck driver presented with history of fever & cough since 3 weeks, progressive fatigue and weight loss of about 10 Kg during the last 6 months. O/E: He had generalized lymphadenopathy, warts on hands and genitals. CNS: Neck stiffness +, Kernig’s sign positive. RS: Crepitations +. He died after 2 days.

• a) What is your diagnosis
• b) Explain the etiopathogenesis of the condition.
• c) What is the probable cause of death

8.Autophagy

9.HIV associated changes in immune function

10.Pathogenises of CNS lesions seen in HIV infection

1.Name two opportunistic viral infection seen in AIDS