Neuromuscular Disorders

1.A 65-year-old post menopausal female presents with weakness in right half of the body with deviation of angle mouth to left side. On examination right side spasticity present and plantar extensor

• a) What is the probable diagnosis and site of lesion
• b) What is the etiopathology of this diagnosis
• c) Describe other clinical signs of this condition
• d) How will you confirm the diagnosis
• e) How will you manage this condition

2.A 70 years old man presents with a history of slowness of movement and tremors of the left hand. On examination patient has mask like facies, coarse tremors of the left hand and rigidity. Answer the following:

• a) What is your probable diagnosis
• b) What are the likely causes for this condition
• c) Where is the lesion.
• d) How will you treat this condition

3.A 30 years lady presents with tingling and numbness of legs and fatigue. On examination she has severe pallor. On examination of CNS, patient is found to have absent ankle jerk and up going plantar bilaterally. Answer the following

• a) What is your probable diagnosis.
• b) What are the probable causes for this condition.
• c) How will you confirm the diagnosis.
• d) How will you treat this condition

1.Myasthenia gravis

1.Causes of peripheral neuropathy

2.Bell’s palsy

3.Classify diabetic neuropathy

4.Draw cross section of spinal cord and label the tracts

5.Causes of myopathy

6.Symptoms of myasthenia gravis

7.Diagnostic criteria of Guillain Barre Syndrome

8.Drugs for neuropathic pain

9.Management of Guillian Barre syndrome

10.What are the symptoms and signs of diabetic peripheral neuropathy

11.Pathogenesis of Myasthenia gravis

12.Duchenne muscular dystrophy

13.Immunological treatment of myasthenia gravis

14.Differences between spasticity and rigidity