Immunization & Cold Chain

1.It was noticed that three children of 1½ years of age presented to a PHC with complaints of swelling on the injection site over lateral aspect of mid-thigh after vaccination. All children took vaccine from the same vaccination session conducted in a subcentre. As a medical officer of the PHC what are the measures you will take to tackle the situation

2.Kamala, 10-year-old girl is admitted in a district hospital with weakness of lower limbs. As a district immunization officer / RCH officer. What are the measures you will take at the individual level and community level in this case

3.Following a vaccination in your Primary Health Centre, many kids developed acute onset of seizure, alteration in level of consciousness within 24 hours of receiving the vaccine. As a medical officer, you are requested to investigate this.

• a) What is this event known as
• b) How will you categorize such events based on cause
• c) Outline the investigation of such event Problems

4.A primary health center reports episodes of fever and swelling following a routine immunization of children and you are required to investigate the matter. Answer the following.

• a) How will you determine that this is in fact an adverse event following immunization (AEFI).
• b) How will you proceed with the investigations. Problems

5.As a medical officer of primary health centre, how will you ensure adequate immunization coverage among under fives in the PHC area

1.Write in brief about Adverse events following immunization

1.Cold chain equipment’s available in PHC

2.Vaccine vial monitor

3.Cold chain equipment used in the universal immunization programme

4.Cold chain equipments present in a primary health centre

5.Contraindications for a Live attenuated vaccine

6.Explain Intensified Mission Indradhanush vaccination campaign under the following

• a) Purpose of the campaign
• b) Beneficiaries
• c) Campaign sites for effective coverage

7.List four live vaccine preventable diseases

8.Maintenance of cold chain is extremely important for a successful vaccination campaign

9.Special immunization campaigns like Mission Indradhanush are needed for achieving full immunization coverage among infants

10.Active and passive immunization

11.Pentavalent vaccine

12.Vaccines to be administered in the first year of life

13.Active and passive immunization Substantiate your answer with reasons

14.Immunization against killer diseases of the childhood is cost effective

1.Common side effects of Pentavalent vaccine

1.All the following are cold chain equipment’s except

• a) Vaccine Carrier
• b) Walk in coolers
• c) Walk in freezers
• d) Refrigerators

2.All the following are true regarding BCG vaccine except

• a) Diluent used is Normal saline
• b) The strain used is Danish 1331
• c) Needs to be repeated if scar is not present
• d) Newborns are given 0.05ml

3.An example of a live attenuated vaccine is

• a) Hepatitis B
• b) Pertussis
• c) Measles
• d) Diphtheria

4.Assertion: The best time to give HPV vaccination is between 9-13 years

• Reason: For the HPV vaccine to work best, it is very important to get all doses before being exposed to HPV
• a) Both A and R are true and R is the correct explanation of A
• b) Both A and R are true but R is not the correct explanation of A
• c) A is true, but R is false
• d) A is false, but R is true

5.The duration of electricity supply required in a day to keep the vaccines effective in an ice-lines refrigerator (ILR) is

• a) 4 hours
• b) 10 hours
• c) 8 hours
• d) 2 hours

6.The Ice lined refrigerator at the PHC maintains a cabinet temperature between

• a) +2°C and +8°C
• b) +8°C and +10°C
• c) -2°C and -8°C
• d) -8°C and -10°C

7.The smartphone app that collects and analyzes information on vaccine stocks and temperatures in India is

• a) Electronic Vaccine Intelligence Network (eVIN)
• b) Automated Vaccine Intelligence Network (aVIN)
• c) CoWIN (Covid Vaccine Intelligence Network)
• d) Integrated Vaccine Intelligence Network (iVIN)

8.What does it indicate

• a) Vaccine is expired
• b) Vaccine is exposed to temperature above 80C over along period of time
• c) Vaccine is contaminated
• d) Vaccine is safe to use

9.What is recommended action

• a) Discard the vaccine
• b) Put the vaccine back in ILR
• c) Vaccine can be used within one hour
• d) Vaccine should be used immediately